Principal Investigator- Clinical Research

Principal Investigator (MD/DO) Miami–Fort Lauderdale Area | Full-Time | On-Site

Spanish fluency required

The Opportunity

We are partnered with one of the top clinical research site networks in the United States, seeking a Principal Investigator to join its South Florida team . Fluency in Spanish is required.

The organization works with leading pharmaceutical and biotechnology companies on Phase I–IV clinical trials.

For physicians looking to build a long-term career in research, this position offers the opportunity to lead industry-sponsored studies with the resources and support of a nationally recognized network. You will provide medical oversight, guide study teams, and remain directly involved in participant care, supported by dedicated staff across study operations and regulatory functions.

Both current Principal Investigators and physicians with Sub-Investigator experience are encouraged to apply. Prior PI experience is preferred, but not required.

Key Responsibilities

• Provide medical leadership and oversight for assigned clinical trials, ensuring participant safety and quality study conduct.
• Evaluate participant eligibility, perform protocol-required medical assessments, and oversee informed consent.
• Assess adverse events and guide clinical decisions throughout study participation.
• Ensure compliance with study protocols, ICH-GCP, FDA regulations, and applicable requirements.
• Provide medical guidance to research staff and collaborate with sponsors, CROs, and monitors.
• Review study documentation and support enrollment, data quality, and overall study execution.

Required Qualifications

• MD or DO degree from an accredited institution.
• At least one year of clinical research experience as a Principal Investigator, Sub-Investigator, or research physician.
• Fluency in Spanish.
• Active Florida medical license or ability to obtain licensure.
• DEA registration or ability to obtain it.
• Working knowledge of ICH-GCP and clinical research regulations.
• Strong clinical judgment and the ability to work collaboratively with research teams.

Preferred Experience

• Principal Investigator experience on industry-sponsored clinical trials.
• Research experience in CNS, psychiatry, neurology, dermatology, gastroenterology, pain, or related therapeutic areas.
• Experience working with sponsors and CROs and supporting study enrollment.

What the Organization Offers

• An established research platform: A national network with longstanding sponsor relationships and a portfolio of industry-sponsored studies.
• Experienced support teams: Clinical operations, regulatory, and research staff supporting study delivery.
• Continued investigator development: The opportunity to build PI experience and pursue long-term career growth within a growing organization.
• Compensation and benefits: Competitive compensation, medical, dental, vision, and retirement benefits.